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  • Anti-Cleaved PARP Monoclonal Antibody
產(chǎn)品名稱：

Anti-Cleaved PARP Monoclonal Antibody
產(chǎn)品品牌： SOLARBIO/索萊寶 價(jià)格：
廠商性質(zhì)： 生產(chǎn)廠家 產(chǎn)品時(shí)間： 2022-08-15
Anti-Cleaved PARP Monoclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:1000-3000.
交叉反應(yīng)Human

產(chǎn)品概述

品牌SOLARBIO/索萊寶貨號(hào)K200027M
規(guī)格50ul/100ul供貨周期現(xiàn)貨
主要用途WB應(yīng)用領(lǐng)域醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)業(yè)

Anti-Cleaved PARP Monoclonal Antibody 

英文名稱Anti-Cleaved PARP Monoclonal Antibody
宿主Mouse
別名PARP-1; Poly(ADP ribose) polymerase 1; sPARP1;ADPRT1; ADP ribosyltransferase NAD(+)
應(yīng)用WB
稀釋比例WB 1:1000-3000.
交叉反應(yīng)Human
蛋白分子量116kDa(Pro)89kDa(Active)
Gene ID142
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG1
免疫原A synthetic peptide coupled to KLH
性狀液體
Public Immunogen Range

A synthetic peptide coupled to KLH

Subcellular LocationsNucleus
Swiss ProtP09874
克隆號(hào)M4
克隆類型Monoclonal Antibody
背景資料Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate.

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